MedChem Express

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MedChemExpress has an experienced team of custom synthesis chemists, led by an impressive group of Ph.D.'s. With this team, we have the capability of supporting all kinds of chemistry projects of multiple step syntheses of complex labeled molecules, including metabolites and steroids. Following scientific and technological innovation, challenging traditional thinking, MedChemExpress has always been committed to develop quality products that exceed international standards on cost and reliability, to create the most advanced synthetic route. With high experiences in preparing a large numbers of different biologically active molecules, we provide rapid synthesis of new products. That is why we can consistently deliver your custom synthesis compounds faster than any other company.

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Voclosporin 50mg  | ≥98%

MedChem Express

Voclosporin is a calcineurin (CN) inhibitor. IC50 & Target: Calcineurin[1] In Vitro: This novel semi-synthetic calcineurin (CN) inhibitor is designated Voclosporin (ISATX247). The efficacy of Voclosporin as an immunosuppressive agent is examined using an in vitro calcineurin assay[1]. Voclosporin (ISATX247) is a calcineurin inhibitor that has shown more potency than Cyclosporine in vitro[2]. In Vivo: […]

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Vofopitant 5mg  | ≥98%

MedChem Express

Vofopitant is potent tachykinin NK1 receptor antagonist, with pKis of 10.6, 9.5, and 9.8 for human, rat and ferret NK1 receptor, respectively. IC50 & Target: pKi: 10.6 (Human NK1 receptor), 9.5 (Rat NK1 receptor), 9.8 (Ferret NK1 receptor)[1] In Vitro: Vofopitant is potent tachykinin NK1 receptor antagonist, with pKis of 10.6, 9.5, and 9.8 for […]

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Vofopitant 10mg  | ≥98%

MedChem Express

Vofopitant is potent tachykinin NK1 receptor antagonist, with pKis of 10.6, 9.5, and 9.8 for human, rat and ferret NK1 receptor, respectively. IC50 & Target: pKi: 10.6 (Human NK1 receptor), 9.5 (Rat NK1 receptor), 9.8 (Ferret NK1 receptor)[1] In Vitro: Vofopitant is potent tachykinin NK1 receptor antagonist, with pKis of 10.6, 9.5, and 9.8 for […]

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Vofopitant 25mg  | ≥98%

MedChem Express

Vofopitant is potent tachykinin NK1 receptor antagonist, with pKis of 10.6, 9.5, and 9.8 for human, rat and ferret NK1 receptor, respectively. IC50 & Target: pKi: 10.6 (Human NK1 receptor), 9.5 (Rat NK1 receptor), 9.8 (Ferret NK1 receptor)[1] In Vitro: Vofopitant is potent tachykinin NK1 receptor antagonist, with pKis of 10.6, 9.5, and 9.8 for […]

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Voglibose 100mg  | ≥98%

MedChem Express

Voglibose is an N-substituted derivative of valiolamine, excellent inhibitory activity against α-glucosidases and its action against hyperglycemia and various disorders caused by hyperglycemia. Target: α-glucosidases glibose can inhibit the intestinal α-glucosidases, which are responsible for the digestion of disaccharides such as maltose and sucrose, including maltase and sucrase. The Ki values of Voglibose for sucrase […]

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Voglibose 50mg  | ≥98%

MedChem Express

Voglibose is an N-substituted derivative of valiolamine, excellent inhibitory activity against α-glucosidases and its action against hyperglycemia and various disorders caused by hyperglycemia. Target: α-glucosidases glibose can inhibit the intestinal α-glucosidases, which are responsible for the digestion of disaccharides such as maltose and sucrose, including maltase and sucrase. The Ki values of Voglibose for sucrase […]

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Voglibose 10mM/1mL  | ≥98%

MedChem Express

Voglibose is an N-substituted derivative of valiolamine, excellent inhibitory activity against α-glucosidases and its action against hyperglycemia and various disorders caused by hyperglycemia. Target: α-glucosidases glibose can inhibit the intestinal α-glucosidases, which are responsible for the digestion of disaccharides such as maltose and sucrose, including maltase and sucrase. The Ki values of Voglibose for sucrase […]

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Volasertib 10mM/1mL  | ≥98%

MedChem Express

Volasertib is a highly potent PLK1 inhibitor with an IC50 of 0.87 nM, as well as the two closely related kinases Plk2 and Plk3 with IC50 values of 5 and 56 nM, respectively. IC50 & Target: IC50: 0.87 nM (PLK1), 5 nM (PLK2), 56 nM (PLK3)[3] In Vitro: Volasertib is potent against HeLa and Caski […]

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Volasertib 5mg  | ≥98%

MedChem Express

Volasertib is a highly potent PLK1 inhibitor with an IC50 of 0.87 nM, as well as the two closely related kinases Plk2 and Plk3 with IC50 values of 5 and 56 nM, respectively. IC50 & Target: IC50: 0.87 nM (PLK1), 5 nM (PLK2), 56 nM (PLK3)[3] In Vitro: Volasertib is potent against HeLa and Caski […]

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Volasertib 10mg  | ≥98%

MedChem Express

Volasertib is a highly potent PLK1 inhibitor with an IC50 of 0.87 nM, as well as the two closely related kinases Plk2 and Plk3 with IC50 values of 5 and 56 nM, respectively. IC50 & Target: IC50: 0.87 nM (PLK1), 5 nM (PLK2), 56 nM (PLK3)[3] In Vitro: Volasertib is potent against HeLa and Caski […]

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Volasertib 50mg  | ≥98%

MedChem Express

Volasertib is a highly potent PLK1 inhibitor with an IC50 of 0.87 nM, as well as the two closely related kinases Plk2 and Plk3 with IC50 values of 5 and 56 nM, respectively. IC50 & Target: IC50: 0.87 nM (PLK1), 5 nM (PLK2), 56 nM (PLK3)[3] In Vitro: Volasertib is potent against HeLa and Caski […]

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Volasertib 100mg  | ≥98%

MedChem Express

Volasertib is a highly potent PLK1 inhibitor with an IC50 of 0.87 nM, as well as the two closely related kinases Plk2 and Plk3 with IC50 values of 5 and 56 nM, respectively. IC50 & Target: IC50: 0.87 nM (PLK1), 5 nM (PLK2), 56 nM (PLK3)[3] In Vitro: Volasertib is potent against HeLa and Caski […]

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Volinanserin 10mg  | ≥98%

MedChem Express

Volinanserin is a potent and selective antagonist of 5-HT2 receptor, with a Ki of 0.36 nM, and shows 300-fold selectivity for 5-HT2 receptor over 5-HT1c, alpha-1 and DA D2 receptors. Volinanserin has antipsychotic activity. IC50 & Target: Ki: 0.36 nM (5-HT2 receptor)[1] In Vitro: Volinanserin (MDL 100907) is a potent antagonist at the 5-HT2 receptor, […]

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Volinanserin 50mg  | ≥98%

MedChem Express

Volinanserin is a potent and selective antagonist of 5-HT2 receptor, with a Ki of 0.36 nM, and shows 300-fold selectivity for 5-HT2 receptor over 5-HT1c, alpha-1 and DA D2 receptors. Volinanserin has antipsychotic activity. IC50 & Target: Ki: 0.36 nM (5-HT2 receptor)[1] In Vitro: Volinanserin (MDL 100907) is a potent antagonist at the 5-HT2 receptor, […]

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Volinanserin 5mg  | ≥98%

MedChem Express

Volinanserin is a potent and selective antagonist of 5-HT2 receptor, with a Ki of 0.36 nM, and shows 300-fold selectivity for 5-HT2 receptor over 5-HT1c, alpha-1 and DA D2 receptors. Volinanserin has antipsychotic activity. IC50 & Target: Ki: 0.36 nM (5-HT2 receptor)[1] In Vitro: Volinanserin (MDL 100907) is a potent antagonist at the 5-HT2 receptor, […]

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Volinanserin 25mg  | ≥98%

MedChem Express

Volinanserin is a potent and selective antagonist of 5-HT2 receptor, with a Ki of 0.36 nM, and shows 300-fold selectivity for 5-HT2 receptor over 5-HT1c, alpha-1 and DA D2 receptors. Volinanserin has antipsychotic activity. IC50 & Target: Ki: 0.36 nM (5-HT2 receptor)[1] In Vitro: Volinanserin (MDL 100907) is a potent antagonist at the 5-HT2 receptor, […]

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Volinanserin 10mM/1mL  | ≥98%

MedChem Express

Volinanserin is a potent and selective antagonist of 5-HT2 receptor, with a Ki of 0.36 nM, and shows 300-fold selectivity for 5-HT2 receptor over 5-HT1c, alpha-1 and DA D2 receptors. Volinanserin has antipsychotic activity. IC50 & Target: Ki: 0.36 nM (5-HT2 receptor)[1] In Vitro: Volinanserin (MDL 100907) is a potent antagonist at the 5-HT2 receptor, […]

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Vorapaxar 5mg  | ≥98%

MedChem Express

Vorapaxar is a thrombin receptor (protease-activated receptor, PAR-1) antagonist. Target: PAR-1 Vorapaxar is an oral protease-activated receptor antagonist, is a novel antiplatelet drug that has been recently approved to provide further risk reduction. Vorapaxar has a high bioavailability after oral administration of >90% with a half-life of 126 h-296 h. It binds reversibly to a […]

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Vorapaxar 10mg  | ≥98%

MedChem Express

Vorapaxar is a thrombin receptor (protease-activated receptor, PAR-1) antagonist. Target: PAR-1 Vorapaxar is an oral protease-activated receptor antagonist, is a novel antiplatelet drug that has been recently approved to provide further risk reduction. Vorapaxar has a high bioavailability after oral administration of >90% with a half-life of 126 h-296 h. It binds reversibly to a […]

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Vorapaxar 5mg  | ≥98%

MedChem Express

Vorapaxar is a thrombin receptor (protease-activated receptor, PAR-1) antagonist. Target: PAR-1 Vorapaxar is an oral protease-activated receptor antagonist, is a novel antiplatelet drug that has been recently approved to provide further risk reduction. Vorapaxar has a high bioavailability after oral administration of >90% with a half-life of 126 h-296 h. It binds reversibly to a […]

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Vorapaxar 50mg  | ≥98%

MedChem Express

Vorapaxar is a thrombin receptor (protease-activated receptor, PAR-1) antagonist. Target: PAR-1 Vorapaxar is an oral protease-activated receptor antagonist, is a novel antiplatelet drug that has been recently approved to provide further risk reduction. Vorapaxar has a high bioavailability after oral administration of >90% with a half-life of 126 h-296 h. It binds reversibly to a […]

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Vorapaxar 10mM/1mL  | ≥98%

MedChem Express

Vorapaxar is a thrombin receptor (protease-activated receptor, PAR-1) antagonist. Target: PAR-1 Vorapaxar is an oral protease-activated receptor antagonist, is a novel antiplatelet drug that has been recently approved to provide further risk reduction. Vorapaxar has a high bioavailability after oral administration of >90% with a half-life of 126 h-296 h. It binds reversibly to a […]

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Vorasidenib 10mM/1mL  | ≥98%

MedChem Express

Vorasidenib is a pan isocitrate dehydrogenase (IDH) inhibitor. IC50 & Target: IDH[1] In Vitro: Vorasidenib has recently entered phase 1 clinical trials in hematologic (NCT02492737) and solid malignancies (NCT02481154) in patients with either an IDH1 or an IDH2 mutation. Preclinical studies have suggested that Vorasidenib fully penetrates the blood-brain barrier and may be a more […]

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Vorasidenib 2mg  | ≥98%

MedChem Express

Vorasidenib is a pan isocitrate dehydrogenase (IDH) inhibitor. IC50 & Target: IDH[1] In Vitro: Vorasidenib has recently entered phase 1 clinical trials in hematologic (NCT02492737) and solid malignancies (NCT02481154) in patients with either an IDH1 or an IDH2 mutation. Preclinical studies have suggested that Vorasidenib fully penetrates the blood-brain barrier and may be a more […]

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Vorasidenib 5mg  | ≥98%

MedChem Express

Vorasidenib is a pan isocitrate dehydrogenase (IDH) inhibitor. IC50 & Target: IDH[1] In Vitro: Vorasidenib has recently entered phase 1 clinical trials in hematologic (NCT02492737) and solid malignancies (NCT02481154) in patients with either an IDH1 or an IDH2 mutation. Preclinical studies have suggested that Vorasidenib fully penetrates the blood-brain barrier and may be a more […]

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Vorasidenib 10mg  | ≥98%

MedChem Express

Vorasidenib is a pan isocitrate dehydrogenase (IDH) inhibitor. IC50 & Target: IDH[1] In Vitro: Vorasidenib has recently entered phase 1 clinical trials in hematologic (NCT02492737) and solid malignancies (NCT02481154) in patients with either an IDH1 or an IDH2 mutation. Preclinical studies have suggested that Vorasidenib fully penetrates the blood-brain barrier and may be a more […]

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Vorasidenib 50mg  | ≥98%

MedChem Express

Vorasidenib is a pan isocitrate dehydrogenase (IDH) inhibitor. IC50 & Target: IDH[1] In Vitro: Vorasidenib has recently entered phase 1 clinical trials in hematologic (NCT02492737) and solid malignancies (NCT02481154) in patients with either an IDH1 or an IDH2 mutation. Preclinical studies have suggested that Vorasidenib fully penetrates the blood-brain barrier and may be a more […]

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Vorasidenib 100mg  | ≥98%

MedChem Express

Vorasidenib is a pan isocitrate dehydrogenase (IDH) inhibitor. IC50 & Target: IDH[1] In Vitro: Vorasidenib has recently entered phase 1 clinical trials in hematologic (NCT02492737) and solid malignancies (NCT02481154) in patients with either an IDH1 or an IDH2 mutation. Preclinical studies have suggested that Vorasidenib fully penetrates the blood-brain barrier and may be a more […]

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Voreloxin 50mg  | ≥98%

MedChem Express

Voreloxin is a first-in-class topoisomerase II inhibitor that intercalates DNA and induces site-selective DNA DSB, G2 arrest, and apoptosis. In Vitro: Voreloxin is a first-in-class topoisomerase II poison and inhibitor that intercalates DNA and induces site-selective DNA DSB, G2 arrest, and apoptosis. Voreloxin (0.1-20 µM) inhibits topoisomerase II activity and induces site-selective DNA DSB in […]

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Voreloxin 5mg  | ≥98%

MedChem Express

Voreloxin is a first-in-class topoisomerase II inhibitor that intercalates DNA and induces site-selective DNA DSB, G2 arrest, and apoptosis. In Vitro: Voreloxin is a first-in-class topoisomerase II poison and inhibitor that intercalates DNA and induces site-selective DNA DSB, G2 arrest, and apoptosis. Voreloxin (0.1-20 µM) inhibits topoisomerase II activity and induces site-selective DNA DSB in […]

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Voreloxin 10mg  | ≥98%

MedChem Express

Voreloxin is a first-in-class topoisomerase II inhibitor that intercalates DNA and induces site-selective DNA DSB, G2 arrest, and apoptosis. In Vitro: Voreloxin is a first-in-class topoisomerase II poison and inhibitor that intercalates DNA and induces site-selective DNA DSB, G2 arrest, and apoptosis. Voreloxin (0.1-20 µM) inhibits topoisomerase II activity and induces site-selective DNA DSB in […]

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Voreloxin (Hydrochloride) 10mM/1mL  | ≥98%

MedChem Express

Voreloxin Hydrochloride is a first-in-class topoisomerase II inhibitor that intercalates DNA and induces site-selective DNA DSB, G2 arrest, and apoptosis. IC50 & Target: Topoisomerase II[1] In Vitro: Voreloxin Hydrochloride is a first-in-class topoisomerase II poison and inhibitor that intercalates DNA and induces site-selective DNA DSB, G2 arrest, and apoptosis. Voreloxin (0.1-20 µM) inhibits topoisomerase II […]

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Voreloxin (Hydrochloride) 5mg  | ≥98%

MedChem Express

Voreloxin Hydrochloride is a first-in-class topoisomerase II inhibitor that intercalates DNA and induces site-selective DNA DSB, G2 arrest, and apoptosis. IC50 & Target: Topoisomerase II[1] In Vitro: Voreloxin Hydrochloride is a first-in-class topoisomerase II poison and inhibitor that intercalates DNA and induces site-selective DNA DSB, G2 arrest, and apoptosis. Voreloxin (0.1-20 µM) inhibits topoisomerase II […]

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Voreloxin (Hydrochloride) 10mg  | ≥98%

MedChem Express

Voreloxin Hydrochloride is a first-in-class topoisomerase II inhibitor that intercalates DNA and induces site-selective DNA DSB, G2 arrest, and apoptosis. IC50 & Target: Topoisomerase II[1] In Vitro: Voreloxin Hydrochloride is a first-in-class topoisomerase II poison and inhibitor that intercalates DNA and induces site-selective DNA DSB, G2 arrest, and apoptosis. Voreloxin (0.1-20 µM) inhibits topoisomerase II […]

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Voriconazole 100mg  | ≥98%

MedChem Express

Voriconazole(UK-109496) is a second-generation triazole antifungal used to treat serious fungal infections. IC50 Value: Target: Antifungal Voriconazole displays potent activity against Candida, Cryptococcus and Aspergillus species. Voriconazole inhibits ergosterol synthesis by inhibiting CYP450-dependent 14-α sterol demethylase resulting in a depletion of ergosterol in fungal cell membranes.

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Voriconazole 50mg  | ≥98%

MedChem Express

Voriconazole(UK-109496) is a second-generation triazole antifungal used to treat serious fungal infections. IC50 Value: Target: Antifungal Voriconazole displays potent activity against Candida, Cryptococcus and Aspergillus species. Voriconazole inhibits ergosterol synthesis by inhibiting CYP450-dependent 14-α sterol demethylase resulting in a depletion of ergosterol in fungal cell membranes.

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Voriconazole 10mM/1mL  | ≥98%

MedChem Express

Voriconazole(UK-109496) is a second-generation triazole antifungal used to treat serious fungal infections. IC50 Value: Target: Antifungal Voriconazole displays potent activity against Candida, Cryptococcus and Aspergillus species. Voriconazole inhibits ergosterol synthesis by inhibiting CYP450-dependent 14-α sterol demethylase resulting in a depletion of ergosterol in fungal cell membranes.

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Vorinostat 250mg  | ≥98%

MedChem Express

Vorinostat is a potent and orally available inhibitor of HDAC1, HDAC2 and HDAC3 (Class I), HDAC7 (Class II) and Class IV (HDAC11), with ID50 values of 10 nM and 20 nM for HDAC1/3, respectively. IC50 & Target: ID50: 10 nM (HDAC1), 20 nM (HDAC3)[3] HDAC2, HDAC7[1], HDAC11[4] In Vitro: Vorinostat efficiently suppresses MES-SA cell growth […]

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Vorinostat 5g  | ≥98%

MedChem Express

Vorinostat is a potent and orally available inhibitor of HDAC1, HDAC2 and HDAC3 (Class I), HDAC7 (Class II) and Class IV (HDAC11), with ID50 values of 10 nM and 20 nM for HDAC1/3, respectively. IC50 & Target: ID50: 10 nM (HDAC1), 20 nM (HDAC3)[3] HDAC2, HDAC7[1], HDAC11[4] In Vitro: Vorinostat efficiently suppresses MES-SA cell growth […]

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Vorinostat 1g  | ≥98%

MedChem Express

Vorinostat is a potent and orally available inhibitor of HDAC1, HDAC2 and HDAC3 (Class I), HDAC7 (Class II) and Class IV (HDAC11), with ID50 values of 10 nM and 20 nM for HDAC1/3, respectively. IC50 & Target: ID50: 10 nM (HDAC1), 20 nM (HDAC3)[3] HDAC2, HDAC7[1], HDAC11[4] In Vitro: Vorinostat efficiently suppresses MES-SA cell growth […]

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Vorinostat 500mg  | ≥98%

MedChem Express

Vorinostat is a potent and orally available inhibitor of HDAC1, HDAC2 and HDAC3 (Class I), HDAC7 (Class II) and Class IV (HDAC11), with ID50 values of 10 nM and 20 nM for HDAC1/3, respectively. IC50 & Target: ID50: 10 nM (HDAC1), 20 nM (HDAC3)[3] HDAC2, HDAC7[1], HDAC11[4] In Vitro: Vorinostat efficiently suppresses MES-SA cell growth […]

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Vorinostat 10mM/1mL  | ≥98%

MedChem Express

Vorinostat is a potent and orally available inhibitor of HDAC1, HDAC2 and HDAC3 (Class I), HDAC7 (Class II) and Class IV (HDAC11), with ID50 values of 10 nM and 20 nM for HDAC1/3, respectively. IC50 & Target: ID50: 10 nM (HDAC1), 20 nM (HDAC3)[3] HDAC2, HDAC7[1], HDAC11[4] In Vitro: Vorinostat efficiently suppresses MES-SA cell growth […]

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Vortioxetine 10mM/1mL  | ≥98%

MedChem Express

Vortioxetine (Lu AA21004) is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively. IC50 Value: 15nM (5-HT1A); 33nM (5-HT1B); 3.7nM(5-HT3A); 19nM (5-HT7); 1.6 nM(SERT) [1] Target: 5-HT receptor in vitro: Compound 5m (Lu AA21004) was the lead […]

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Vortioxetine 10mg  | ≥98%

MedChem Express

Vortioxetine (Lu AA21004) is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively. IC50 Value: 15nM (5-HT1A); 33nM (5-HT1B); 3.7nM(5-HT3A); 19nM (5-HT7); 1.6 nM(SERT) [1] Target: 5-HT receptor in vitro: Compound 5m (Lu AA21004) was the lead […]

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Vortioxetine 5mg  | ≥98%

MedChem Express

Vortioxetine (Lu AA21004) is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively. IC50 Value: 15nM (5-HT1A); 33nM (5-HT1B); 3.7nM(5-HT3A); 19nM (5-HT7); 1.6 nM(SERT) [1] Target: 5-HT receptor in vitro: Compound 5m (Lu AA21004) was the lead […]

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Vortioxetine 50mg  | ≥98%

MedChem Express

Vortioxetine (Lu AA21004) is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively. IC50 Value: 15nM (5-HT1A); 33nM (5-HT1B); 3.7nM(5-HT3A); 19nM (5-HT7); 1.6 nM(SERT) [1] Target: 5-HT receptor in vitro: Compound 5m (Lu AA21004) was the lead […]

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Vortioxetine (hydrobromide) 5mg  | ≥98%

MedChem Express

Vortioxetine Hcl (Lu AA21004 Hcl) is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively. IC50 Value: 15nM (5-HT1A); 33nM (5-HT1B); 3.7nM(5-HT3A); 19nM (5-HT7); 1.6 nM(SERT) [1] Target: 5-HT receptor in vitro: Compound 5m (Lu AA21004) was […]

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Vortioxetine (hydrobromide) 50mg  | ≥98%

MedChem Express

Vortioxetine Hcl (Lu AA21004 Hcl) is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively. IC50 Value: 15nM (5-HT1A); 33nM (5-HT1B); 3.7nM(5-HT3A); 19nM (5-HT7); 1.6 nM(SERT) [1] Target: 5-HT receptor in vitro: Compound 5m (Lu AA21004) was […]

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Vortioxetine (hydrobromide) 10mg  | ≥98%

MedChem Express

Vortioxetine Hcl (Lu AA21004 Hcl) is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively. IC50 Value: 15nM (5-HT1A); 33nM (5-HT1B); 3.7nM(5-HT3A); 19nM (5-HT7); 1.6 nM(SERT) [1] Target: 5-HT receptor in vitro: Compound 5m (Lu AA21004) was […]

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Vortioxetine (hydrobromide) 10mM/1mL  | ≥98%

MedChem Express

Vortioxetine Hcl (Lu AA21004 Hcl) is a multimodal serotonergic agent, inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively. IC50 Value: 15nM (5-HT1A); 33nM (5-HT1B); 3.7nM(5-HT3A); 19nM (5-HT7); 1.6 nM(SERT) [1] Target: 5-HT receptor in vitro: Compound 5m (Lu AA21004) was […]

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