AdipoGen Life Sciences

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AdipoGen Life Sciences develops and manufactures new products for the Life Science Research Market in the key areas of cancer, immunology, inflammation, metabolic syndrome (diabetes, obesity), stem cell biology, and neurodegeneration. The product portfolio consists of antibodies, proteins, ELISA Kits and innovative small molecules. The chemical portfolio includes, rare antibiotics, unique natural products, synthetic kinase modulators, fluorescent probes and much more.

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TRITC 250 mg  | >95%

AdipoGen Life Sciences

5(6)-TRITC is spectrally similar to TAMRA. The isothiocyanate reactive group reacts with primary or secondary amines to form a thiourea bond linkage.

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Troglitazone 5 mg  | >98%

AdipoGen Life Sciences

Potent and selective PPARgamma agonist with no activation of PPARalpha and PPARdelta. Anti-diabetic agent with potent glucose-lowering effects and decreasing insulin resistance in adipose tissues. Stimulates adipogenesis. Apoptosis and cell cycle arrest inducer in several cancer cell lines. Anti-inflammatory. Inhibits vascular smooth muscle cell (VSMC) migration.

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Troglitazone 25 mg  | >98%

AdipoGen Life Sciences

Potent and selective PPARgamma agonist with no activation of PPARalpha and PPARdelta. Anti-diabetic agent with potent glucose-lowering effects and decreasing insulin resistance in adipose tissues. Stimulates adipogenesis. Apoptosis and cell cycle arrest inducer in several cancer cell lines. Anti-inflammatory. Inhibits vascular smooth muscle cell (VSMC) migration.

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Trolox 500 mg  | >98%

AdipoGen Life Sciences

Cell permeable and water soluble derivative of vitamin E. Potent antioxidant. Efficiently prevents formation of different reactive oxygen species, such as singlet oxygen (1O2), superoxide anion (O2-) or hydrogen peroxide (H2O2). Commonly used as a standard or positive control in different antioxidant assays, such as ABTS decolorization and FRAP assays, measuring Trolox equivalent antioxidant capacity […]

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Trolox 1 g  | >98%

AdipoGen Life Sciences

Cell permeable and water soluble derivative of vitamin E. Potent antioxidant. Efficiently prevents formation of different reactive oxygen species, such as singlet oxygen (1O2), superoxide anion (O2-) or hydrogen peroxide (H2O2). Commonly used as a standard or positive control in different antioxidant assays, such as ABTS decolorization and FRAP assays, measuring Trolox equivalent antioxidant capacity […]

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Trolox 5 g  | >98%

AdipoGen Life Sciences

Cell permeable and water soluble derivative of vitamin E. Potent antioxidant. Efficiently prevents formation of different reactive oxygen species, such as singlet oxygen (1O2), superoxide anion (O2-) or hydrogen peroxide (H2O2). Commonly used as a standard or positive control in different antioxidant assays, such as ABTS decolorization and FRAP assays, measuring Trolox equivalent antioxidant capacity […]

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Tropodithietic acid [TDA] 1 mg  | >98%

AdipoGen Life Sciences

Antibiotic. Isomeric to thiotropocin. Antibacterial. Active against Gram-positive and Gram-negative bacteria. Antifungal and anti-nematodical. Shows antitumor activity. Cytotoxic against selected mammalian neuronal cell lines. Bacterial signal substance.

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Tropodithietic acid [TDA] 5 mg  | >98%

AdipoGen Life Sciences

Antibiotic. Isomeric to thiotropocin. Antibacterial. Active against Gram-positive and Gram-negative bacteria. Antifungal and anti-nematodical. Shows antitumor activity. Cytotoxic against selected mammalian neuronal cell lines. Bacterial signal substance.

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Trypacidin 1 mg  | >98%

AdipoGen Life Sciences

Antibiotic. Antibacterial and antiprotozoal (trypanocidal). Toxic to human A549 lung cells. Necrosis inducer. Toxic to human bronchial epithelial cells. Stimulating the growth of corn seedling roots. Inhibits IL-6 secretion, collagen IV and fibronectin production

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Trypacidin 5 mg  | >98%

AdipoGen Life Sciences

Antibiotic. Antibacterial and antiprotozoal (trypanocidal). Toxic to human A549 lung cells. Necrosis inducer. Toxic to human bronchial epithelial cells. Stimulating the growth of corn seedling roots. Inhibits IL-6 secretion, collagen IV and fibronectin production

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Tubastatin A 10 mg  | >98%

AdipoGen Life Sciences

Cell permeable potent and selective class IIb histone deacetylase 6 (HDAC6) inhibitor (IC50=15nM, >1000-fold selective against other HDACs and 60-fold for HDAC8). Neuroprotective. Effectively prevents neuronal cell death (by >95% at 10µM) upon oxidative stress induction by HCA and selectively induces cellular alpha-tubulin, but not histone H4, hyperacetylation (2.5 to 5µM) in primary rat cortical […]

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UK-1 250 µg  | >98%

AdipoGen Life Sciences

Antibiotic. Antifungal. Topoisomerase II (Topo II) inhibitor. Mg2+- and Zn2+-dependent DNA binding agent. Potent anticancer compound.

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UK-1 1 mg  | >98%

AdipoGen Life Sciences

Antibiotic. Antifungal. Topoisomerase II (Topo II) inhibitor. Mg2+- and Zn2+-dependent DNA binding agent. Potent anticancer compound.

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Umbellulone 10 mg  | >98%

AdipoGen Life Sciences

Offensive principle of the so-called “headache tree”. Causes a painful cold sensation. Selective TRPA1 activator. Weak TRPM8 activator. Releases CGRP (calcitonin gene-related peptide) after TRPA1 activation which leads to activation of trigeminovascular pathways and CGRP-mediated neurogenic vasodilatation relevant to produce headache/migraine.

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Undecylprodigiosin . hydrochloride 250 µg  | >95%

AdipoGen Life Sciences

Tripyrrolic pigment like prodigiosin. Antimalarial agent. Apoptosis inducer. Anticancer agent with multiple modes of action. Immunosuppressant in non-toxic concentrations. Bone resorption inhibitor. Antiulcer agent.

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Undecylprodigiosin . hydrochloride 1 mg  | >95%

AdipoGen Life Sciences

Tripyrrolic pigment like prodigiosin. Antimalarial agent. Apoptosis inducer. Anticancer agent with multiple modes of action. Immunosuppressant in non-toxic concentrations. Bone resorption inhibitor. Antiulcer agent.

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Ursodeoxycholic acid 1 g  | >95%

AdipoGen Life Sciences

Endogenous hydrophilic bile acid. Antioxidant. Cytoprotective against oxidative stress and cell death. Hepatoprotective at cellular and molecular level, including stabilization of membranes. Protects hepatocytes against bile acid-induced apoptosis. Antiapoptotic and antinecrotic. Targets the mitochondrial function and integrity, reduction of endoplasmatic stress and interactions with survival signals in cAMP, Akt, NF-kappaB, MAPK and PI3K signaling pathways. […]

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Ursodeoxycholic acid 5 g  | >95%

AdipoGen Life Sciences

Endogenous hydrophilic bile acid. Antioxidant. Cytoprotective against oxidative stress and cell death. Hepatoprotective at cellular and molecular level, including stabilization of membranes. Protects hepatocytes against bile acid-induced apoptosis. Antiapoptotic and antinecrotic. Targets the mitochondrial function and integrity, reduction of endoplasmatic stress and interactions with survival signals in cAMP, Akt, NF-kappaB, MAPK and PI3K signaling pathways. […]

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Venturicidin A 1 mg  | >98%

AdipoGen Life Sciences

20-Membered macrolide glycoside. Antibiotic and antifungal agent. Shows antitrypanosomal and antimalarial activity. Potent inhibitor of mitochondrial and bacterial ATP synthase. Inhibitor of F0F1-ATPase. Na+-translocating ATP synthases inhibitor.

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Venturicidin A 5 mg  | >98%

AdipoGen Life Sciences

20-Membered macrolide glycoside. Antibiotic and antifungal agent. Shows antitrypanosomal and antimalarial activity. Potent inhibitor of mitochondrial and bacterial ATP synthase. Inhibitor of F0F1-ATPase. Na+-translocating ATP synthases inhibitor.

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Verruculogen 1 mg  | >98%

AdipoGen Life Sciences

Fumitremorgin-type alkaloid. Tremorgenic neurotoxic mycotoxin. Selective blocker of KCa1.1 (high-conductance Ca2+-activated K+; BK; maxi-K) channels. Decreases GABA levels in CNS. Increases spontaneous glutamate and aspartate release. At toxic doses, increases the number and decreases the affinity of DHP receptors in rat cortex. Cell cycle inhibitor at the M phase. Inhibits calmodulin and PKC activity. Has […]

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Verruculogen 5 mg  | >98%

AdipoGen Life Sciences

Fumitremorgin-type alkaloid. Tremorgenic neurotoxic mycotoxin. Selective blocker of KCa1.1 (high-conductance Ca2+-activated K+; BK; maxi-K) channels. Decreases GABA levels in CNS. Increases spontaneous glutamate and aspartate release. At toxic doses, increases the number and decreases the affinity of DHP receptors in rat cortex. Cell cycle inhibitor at the M phase. Inhibits calmodulin and PKC activity. Has […]

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Vincristine . sulfate 5 mg  | >98%

AdipoGen Life Sciences

Immunosuppressant. Anticancer compound. Chemotherapeutic agent. Depolymerizes microtubules and irreversibly blocks binding of tubulin to microtubule proteins. Apoptosis inducer and cell cycle inhibitor in G2/M phase. Autophagy inhibitor. Inhibits microtubule-mediated fusion of autophagosome with lysosme. Inducer of IL-1beta production. Activates alone and synergistically together with doxorubicin the NLRP3-inflammasome mediated processing of IL-1beta. Monoamine oxidase (MAO) inhibitor.

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Vincristine . sulfate 25 mg  | >98%

AdipoGen Life Sciences

Immunosuppressant. Anticancer compound. Chemotherapeutic agent. Depolymerizes microtubules and irreversibly blocks binding of tubulin to microtubule proteins. Apoptosis inducer and cell cycle inhibitor in G2/M phase. Autophagy inhibitor. Inhibits microtubule-mediated fusion of autophagosome with lysosme. Inducer of IL-1beta production. Activates alone and synergistically together with doxorubicin the NLRP3-inflammasome mediated processing of IL-1beta. Monoamine oxidase (MAO) inhibitor.

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Vinpocetine 20 mg  | >98%

AdipoGen Life Sciences

Selective Ca2+-calmodulin dependent cGMP-phosphodiesterase (PDE1) inhibitor. Shows vasorelaxant activity. Neuroprotective agent. Selectively inhibits voltage-sensitive 2+ channels Potent anti-inflammatory agent. Inhibitor of NF-kappaB-dependent inflammatory responses by directly targeting IKK. Shown to inhibit the NLRP3 inflammasome. Antioxidant. Free radical scavenger. Anticancer compound. Anticonvulsant.

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Vinpocetine 100 mg  | >98%

AdipoGen Life Sciences

Selective Ca2+-calmodulin dependent cGMP-phosphodiesterase (PDE1) inhibitor. Shows vasorelaxant activity. Neuroprotective agent. Selectively inhibits voltage-sensitive 2+ channels Potent anti-inflammatory agent. Inhibitor of NF-kappaB-dependent inflammatory responses by directly targeting IKK. Shown to inhibit the NLRP3 inflammasome. Antioxidant. Free radical scavenger. Anticancer compound. Anticonvulsant.

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Violacein 1 mg  | >97%

AdipoGen Life Sciences

Antibacterial, antifungal and antiprotozoal agent. Quorum sensing metabolite. Antitumor compound. Protective against UV-C irradiation. Possesses immunomodulatory, analgesic and antipyretic activity. Indole-derived purple-colored pigment (free of deoxyviolacein).

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Violacein 5 mg  | >97%

AdipoGen Life Sciences

Antibacterial, antifungal and antiprotozoal agent. Quorum sensing metabolite. Antitumor compound. Protective against UV-C irradiation. Possesses immunomodulatory, analgesic and antipyretic activity. Indole-derived purple-colored pigment (free of deoxyviolacein).

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Viridiol 250 µg  | >95%

AdipoGen Life Sciences

Steroidal antibiotic. Belongs to the Viridin family, including Wortmannin (Prod. No. AG-CN2-0023 http://www.adipogen.com/ag-cn2-0023/wortmannin.html ). Antifungal. Phytotoxin. Shows necrotic activity on plants. Phosphatidylinositol 3-kinase (PI3K) inhibitor.

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Viridiol 1 mg  | >95%

AdipoGen Life Sciences

Steroidal antibiotic. Belongs to the Viridin family, including Wortmannin (Prod. No. AG-CN2-0023 http://www.adipogen.com/ag-cn2-0023/wortmannin.html ). Antifungal. Phytotoxin. Shows necrotic activity on plants. Phosphatidylinositol 3-kinase (PI3K) inhibitor.

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Vitexin 5 mg  | >98%

AdipoGen Life Sciences

alpha-Glucosidase inhibitor. Antioxidant. HIF-1 alpha inhibitor. Anti-metastatic. Apoptosis inducer. Tumor suppressor. Adipogenesis inhibitor. Inhibits SIRT6 in vitro. Inhibits polyubiquitin synthesis by the ubiquitin-conjugating enzyme E2-25K. Cardioprotective. Anti-inflammatory. Shows analgesic effect by targeting TRPV1 channel activity. Neuroprotective. Inhibits NMDA receptors.

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Vitexin 25 mg  | >98%

AdipoGen Life Sciences

alpha-Glucosidase inhibitor. Antioxidant. HIF-1 alpha inhibitor. Anti-metastatic. Apoptosis inducer. Tumor suppressor. Adipogenesis inhibitor. Inhibits SIRT6 in vitro. Inhibits polyubiquitin synthesis by the ubiquitin-conjugating enzyme E2-25K. Cardioprotective. Anti-inflammatory. Shows analgesic effect by targeting TRPV1 channel activity. Neuroprotective. Inhibits NMDA receptors.

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W-5 . hydrochloride 5 mg  | >98%

AdipoGen Life Sciences

Calmodulin antagonist. Cell proliferation inhibitor. Ca2+/calmodulin-regulated phosphodiesterase (PDE I) inhibitor. Myosin light chain kinase (MLCK) inhibitor.

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W-5 . hydrochloride 25 mg  | >98%

AdipoGen Life Sciences

Calmodulin antagonist. Cell proliferation inhibitor. Ca2+/calmodulin-regulated phosphodiesterase (PDE I) inhibitor. Myosin light chain kinase (MLCK) inhibitor.

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Wedelolactone 1 mg  | >98%

AdipoGen Life Sciences

Cell permeable, selective and irreversible IKKalpha and beta kinase activity inhibitor. NF-kappaB inhibitor. Blocks phosphorylation and degradation of IkappaBalpha. Antihepatotoxic. 5-Lipoxygenase (5-LOX) inhibitor. Anti-inflammatory. HIV-1 integrase inhibitor. Anticancer and antiproliferative compound. Modulates androgen receptor (AR) activation. Apoptosis inducer via downregulation of PKCepsilon. DNA topoisomerase IIalpha inhibitor. G protein-coupled receptor-35 (GPR35) agonist. Inhibits adipogenic differentiation of […]

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Wedelolactone 5 mg  | >98%

AdipoGen Life Sciences

Cell permeable, selective and irreversible IKKalpha and beta kinase activity inhibitor. NF-kappaB inhibitor. Blocks phosphorylation and degradation of IkappaBalpha. Antihepatotoxic. 5-Lipoxygenase (5-LOX) inhibitor. Anti-inflammatory. HIV-1 integrase inhibitor. Anticancer and antiproliferative compound. Modulates androgen receptor (AR) activation. Apoptosis inducer via downregulation of PKCepsilon. DNA topoisomerase IIalpha inhibitor. G protein-coupled receptor-35 (GPR35) agonist. Inhibits adipogenic differentiation of […]

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White Line Inducing Principle [WLIP] 1 mg  | >98%

AdipoGen Life Sciences

Lipodepsipeptide (LDP). Used as a diagnostic tool to identify tolaasin-producing bacteria pathogenic to mushrooms and responsible for brown blotch disease. Has haemolytic activity. Permeabilizes lipid vesicles and is involved in mushroom tissue alterations by forming transmembrane pores. Antimicrobial. Antibacterial. Antifungal.

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Withaferin A 1 mg  | >98%

AdipoGen Life Sciences

Multifunctional anticancer compound. Amplifies the cellular antioxidant and/or detoxification system, suppresses inflammatory pathways, selectively inhibits tumor cell proliferation and induces apoptosis, suppresses tumor angiogenesis, blocks epithelial-to-mesenchymal transition (EMT), tumor invasion and metastasis, alters tumor cell metabolism, induces immunomodulation and downregulates cancer stem cells targets. Sensitizes resistant cancer cells to existing chemotherapeutic agents. Antioxidant. Induces cytoprotective […]

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Withaferin A 5 mg  | >98%

AdipoGen Life Sciences

Multifunctional anticancer compound. Amplifies the cellular antioxidant and/or detoxification system, suppresses inflammatory pathways, selectively inhibits tumor cell proliferation and induces apoptosis, suppresses tumor angiogenesis, blocks epithelial-to-mesenchymal transition (EMT), tumor invasion and metastasis, alters tumor cell metabolism, induces immunomodulation and downregulates cancer stem cells targets. Sensitizes resistant cancer cells to existing chemotherapeutic agents. Antioxidant. Induces cytoprotective […]

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Withaferin A 10 mg  | >98%

AdipoGen Life Sciences

Multifunctional anticancer compound. Amplifies the cellular antioxidant and/or detoxification system, suppresses inflammatory pathways, selectively inhibits tumor cell proliferation and induces apoptosis, suppresses tumor angiogenesis, blocks epithelial-to-mesenchymal transition (EMT), tumor invasion and metastasis, alters tumor cell metabolism, induces immunomodulation and downregulates cancer stem cells targets. Sensitizes resistant cancer cells to existing chemotherapeutic agents. Antioxidant. Induces cytoprotective […]

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Wogonin 5 mg  | >98%

AdipoGen Life Sciences

Anti-inflammatory. Increases nitric oxide (NO) production. Inhibits PGE2, cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS; NOS II). Antioxidant. Anti-viral. Shows anti-hepatitis B virus activity. MCP-1 inhibitor. Shows anxiolytic effect through modulation of the GABA(A) receptor complex. Antifungal. Neuroprotective. Anticancer compound. Apoptosis and cell cycle arrest inducer. Sensitizes TNFalpha- and TRAIL-induced apoptosis. Antiangiogenic. NF-kappaB inhibitor. […]

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